Is your sperm count low or absent? Have you been advised ICSI?1 comment drpankajtalwar July 9th, 2019
- Woman is stimulated for follicle production and egg recovery as in IVF.
- Single sperm is taken from male partner’s semen or surgically extracted from his testes or epididymis.
- The mature egg is held with a micropipette.
- Injecting needle is used to immobilize and pick up of a single sperm.
- The needle is then carefully inserted through the shell of the egg and into the ooplasm.
- The sperm is injected into the ooplasm, the needle is carefully removed and oocytes are left for the fertilization in an incubator.
Mostly ICSI is indicated for the cases with:
- Previous failed fertilization.
- When fertilization rate has been unexpectedly poor.
- Patient with surgically retrieved spermatozoa (TESA, PESA and MESA) either for azoospermia or man with high DNA fragmentation.
- Patient who want to go for PGS or PGD
ICSI is a procedure which effectively eliminates male infertility by introducing sperm cell directly into an egg, hence increases chances for fertilization for male factor.
Right choice if you have male factor infertility/ repeated IVF failure.
- ICSI is only choice of method for azoospermic men to become father.
- TESA / TESE ICSI is also preferred for men with high sperm DNA fragmentation, azoospermia and for men with the variable count per ejaculate from a standard laboratory.
ICSI conceived children are not at a higher absolute risk of any disease or illness.
Intracytoplasmic morphologically selected sperm injection (IMSI) is a variation of ICSI that uses a high power microscope to select sperm. This allows embryologists to look at the sperm in greater detail at 6600X magnification.
DNA damage occurs at the post-testicular level, hence testicular sperm may have a better DNA integrity than ejaculated sperm.
One response to “Is your sperm count low or absent? Have you been advised ICSI?”
CK Birla Hospital
Block J, Mayfield Garden Sector 51, Gurugram