Ovarian Reserve Archives - Best IVF Specialist in Gurgaon | Dr Pankaj Talwar | Male Infertility Expert
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Best IVF Specialist Doctor in Delhi, Gurugram

When you think about trying to conceive, your age is probably one of the first things that come to mind. And it’s true that age is a major factor in fertility. But it’s not the only factor. Your age, combined with the age of your eggs, as well as your general health, all play a role in your fertility.

Age

Your age is the most important factor in your fertility. As you age, your eggs age with you.

In your early to mid-20s, you have about a 20% chance of getting pregnant each month.

By age 30, your chance of getting pregnant each month starts to decline.

Your chance of becoming pregnant each month by the age of 35 is only slightly higher than it was in your twenties.

Furthermore, your chance of becoming pregnant each month by the age of 40 is only about 5%.

Egg quality

In addition to your age, the quality of your eggs also plays a role in your fertility. As you age, the quality of your eggs declines. This is why your chance of getting pregnant declines as you age.

The quality of your eggs is measured by something called the anti-Müllerian hormone (AMH). AMH is a hormone produced by the cells that surround your eggs. The higher your AMH level, the higher the quality of your eggs.

General Health

Your general health also plays a role in your fertility. Conditions like obesity, diabetes, and high blood pressure can all impact your fertility.

Making lifestyle changes

There are things you can do to improve your fertility, no matter your age. If you’re a smoker, quitting smoking can improve your fertility. If you’re overweight, losing weight can also improve your fertility.

And if you have a medical condition that’s impacting your fertility, there may be treatments that can help. For example, if you have polycystic ovary syndrome (PCOS), a common cause of infertility, there are treatments that can help you get pregnant.

If you’re having trouble getting pregnant, talk to your doctor. They can help you figure out what might be causing your fertility problems and what you can do about it.

Can you improve AMH levels?

Yes, you can improve your AMH levels. But unfortunately, it’s not as easy as popping a few supplements or taking some drugs.

The good news is that there are several things you can do to naturally boost your AMH levels, including:

  • Get more sleep. A lack of sleep has been linked to reduced fertility in both men and women, so getting enough shut-eye is essential for maintaining a healthy hormone balance.
  • Eat more protein and healthy fats. Protein helps build muscle, which releases growth hormones that help increase bone density and strength. Healthy fats like omega-3s are also important for brain function, which affects the production of hormones like AMH.
  • Exercise regularly — but not too much! Moderate physical activity can help stimulate the production and release of growth hormone, which promotes the development of new cells and tissue growth throughout the body.
    However, excessive exercise can actually suppress your body’s natural supply of growth hormone by releasing cortisol (the stress hormone). So make sure you’re getting enough rest between workouts!
  • Consider taking an herbal supplement that contains vitex agnus castus extract (VAC).

VAC has been shown to increase AMH levels by up to 88% in clinical studies, and it’s been used for hundreds of years to enhance fertility in both men and women.

VAC works by helping the pituitary gland produce more luteinizing hormone (LH), which is then released into the bloodstream and travels onto the testicles where it signals them to produce testosterone.

Final words

There are many factors that play a role in whether or not you’ll get pregnant, and AMH is just one of them. But before you try to conceive, it’s important to work with your doctor to find the right treatment plan for you based on all of your individual factors and preferences.

Endometriosis is a condition wherein tissue like the uterine lining (endometrium) grows somewhere else in the body. Pelvic pain is the most common indication of endometriosis, yet a few women with the condition may likewise encounter infertility.

Endometriosis may develop outside of your uterus, ovaries, and tubes and even on your bladder or digestion tracts. This tissue can irritate structures that it contacts, causing pain and adhesions (scar tissue) on these organs.

Symptoms of Endometriosis

Symptoms can vary with some women not having any at all, and others having very severe pain. The most common symptoms are:

  • Painful, heavy or irregular periods
  • Pain in the lower abdomen, pelvis or lower back around ovulation time, but also throughout the cycle
  • Ongoing pelvic pain lasting six months or longer
  • Pain during or after sex
  • Difficulty getting pregnant
  • Painful bowel movements and emptying of bladder

Impact of Endometriosis on Fertility

On the off chance that you have endometriosis, it might be more difficult for you to get pregnant. Up to 30% to 50 % of females with endometriosis may encounter infertility. Endometriosis can impact fertility in different ways: distorted anatomy of the pelvis, adhesions, scarred fallopian tubes, inflammation of the pelvic structures, altered immune system functioning, changes in the hormonal environment of the eggs, impaired implantation of a pregnancy, and altered egg quality.

At the point when endometrial tissue wraps over your ovaries, it can block your eggs from releasing. The tissue can obstruct sperm from making its way up your fallopian tubes. It can likewise prevent a fertilized egg from sliding down your tubes to your uterus.

Treatment of Endometriosis Related Infertility

In case of difficulty getting pregnant with endometriosis you may wish to consult a fertility specialist. Treatment options for endometriosis related infertility include:

  • Freezing eggs: Endometriosis can influence your ovarian reserve, so a few specialists may suggest protecting your eggs at present on the off chance that you wish to get pregnant later. This choice can be expensive, and isn’t typically covered by insurance.
  • Superovulation and intrauterine insemination (SO-IUI): This is a possibility for women who have normal fallopian tubes, mild endometriosis, and whose partner has good quality sperm.
  • A specialist will prescribe fertility medicines, like, Clomiphene. These medicines help to produce a few mature eggs. A specialist may likewise prescribe a progestin injection.
  • A woman will routinely go through ultrasounds to guarantee the eggs are at their most matured state. At the point when the eggs are ready, a specialist will embed a partner’s collected sperm.
  • In vitro preparation (IVF): This treatment includes extracting an egg from you and sperm from your partner. The egg is then fertilized externally and embedded into the uterus.

The success rates of IVF are 50 percent for women who don’t have endometriosis. But many women with endometriosis have successfully gotten pregnant thanks to IVF treatments. IVF is often recommended for women with moderate to severe endometriosis, or for women whose bodies haven’t responded to other treatments.

Egg banking, also known as oocyte cryopreservation, is a moderately new strategy for fertility protection where a developed, unfertilized egg is retrieved from a female, frozen and stored for later use.

Egg banking includes a female deciding to have eggs retrieved from her ovaries, frozen to preserve their viability and put away until she is ready to utilize them in a future in vitro fertilization (IVF) treatment to achieve pregnancy.

Egg freezing and egg banking can be utilized to preserve fertility in patients having aggressive medical treatments, for example, chemotherapy, or in patients who wish to protect their fertility presently to begin a family later.

Egg freezing process in conjunction with IVF

Egg freezing is achieved through a new IVF cycle, avoiding egg treatment in vitro.

  • Stimulation of a woman’s ovaries utilizing fertility medications to produce a few egg follicles during one new IVF cycle
  • Harvesting eggs from the woman’s ovaries through surgical retrieval
  • Preparing and freezing of the eggs for preservation through a cycle known as vitrification
  • The fast-freezing technique of vitrification makes it possible to freeze eggs rapidly so that ice crystals don’t form between cells

Egg banking in cancer treatment

Egg banking increases opportunities for women going through cancer treatment who preserve their fertility. In the event that they have a partner, they could go through a stimulation and retrieval cycle, developing embryos, and freeze them for some time in the future. They could do likewise without an available partner, in the event that they willing to utilize donor sperm to develop embryos. This would ensure them hereditary offspring, yet with a missing sperm donor father. In the event that they come up short on a partner and ability to utilize a sperm donor, egg freezing would empower as it both secures their fertility and gives them a decision over the genetic father of their post-treatment children. A comparable need may emerge with women with hereditary illnesses or different conditions, for example, premature ovarian failure, who had not yet found a spouse yet needed to ensure they have healthy eggs at a later point in their life for reproduction.

Advantages of egg banking

  • Egg banking permits patients to extend their fertility. Thawed eggs hold their capacity to get fertilized from the time of freezing, giving the patient peace of mind by knowing pregnancy might be conceivable later on.
  • For women who need to through fertility damaging treatments, for example, chemotherapy, egg freezing may permit them to preserve their fertility and start a family after treatment.
  • Egg freezing can likewise assist women with premature fertility loss, for example, reduced ovarian reserve, by banking healthy eggs at an early age when they are likely to be viable for sometime in the future. In these cases, the woman’s doctor will suggest egg freezing and banking.
  • A few women decide to freeze and bank their eggs for social reasons, for example, waiting for the right partner or not wanting to take a leave from work. The frozen eggs can be thawed, fertilized and embedded for pregnancy sometime in the not too distant future.

Risks of egg banking

Egg freezing carries several risks to the woman or couple, including:

  • Ovarian hyperstimulation syndrome (OHSS).
  • Surgical complications.
  • Emotional effects.

IVF is the process of fertilization by extracting eggs, recovering a sperm sample, and afterward physically joining an egg and sperm in a laboratory. The embryo(s) is then moved to the uterus. As indicated by the Society of Assisted Reproductive Technologies (SART), the success rate of giving birth to a live child after IVF is as per the following:

  • 47.8%for females under age 35
  • 38.4% for females age 35 to 37
  • 26% for females ages 38 to 40
  • 13.5% for females age 41 to 42

How are IVF Success Rates Determined and Reported?

Live Birth Rate: Live birth rate is the number of infants born divided by the number of cycles started to accomplish the birth. Remember that this information is generally dated, and patients should remember that doctors are continually refining and improving IVF.

Implantation and Pregnancy Rates: It permits a person to see the number of patients got a positive pregnancy test, the number of clinical pregnancies (checked by ultrasound), as well as the number of miscarriages.

Cycle characteristics: Cycle characteristics include average (mean) number of embryos transferred and the percentage of patients deciding on elective single embryo transfer (eSET).

Factors Affecting IVF Success Rate

Common factors that determine the success of IVF includes the following:

Age

Women age and utilization of own eggs are significant IVF success factors to consider. While young females have higher odds of IVF success, factors that decrease the odds of IVF success incorporate being a older woman with less eggs and the lower quality of a older woman eggs. The live birth IVF success rate for women under 35 who start an IVF cycle is 40%. However, women over age 42 have a 4 percent achievement rate.

Previous Pregnancy

More IVF success factors to consider incorporate whether you were pregnant already and in the event that it was with the same partner. In the event that you were pregnant beforehand with the same partner that is as of now going through IVF treatment, there is a more prominent chance of IVF success. Factors, for example, a background marked recurrent miscarriages or a different partner may decrease the odds of IVF success.

Type of Fertility Problems

While some male infertility issues do affect IVF success, factors like uterine irregularities, exposure to DES or fibroid tumors likewise declines the probability of success with IVF.

Important to know: IVF success factors are reliant on ovulation. Ovarian dysfunction, similar to high FSH levels which demonstrate a low ovarian reserve, may diminish the chance of IVF success. Variables that may bring down pregnancy rates and decrease success with IVF include requiring a lot of ovulation stimulation drugs.

Whenever the two partners are infertile with lower chances for IVF success, factors, for example, the time you have been infertile is imperative to consider. The chances of IVF success decline with the amount of time a couple has been infertile.

Use of Donor Eggs

Donor eggs are a critical consideration, particularly if the women are more than 35-40, as there might be a higher rate of IVF success. Factors, for example, egg quality and age of donor are significant. Utilizing donor eggs from young women may build the chances of pregnancy for women more than 40. 2011 discoveries show a 55 percent live birth achievement rate with a new donor egg/embryo transfer.

Lifestyles Habits

  • Quit smoking to improve your chance of getting pregnant. Usually the woman is needed to quit smoking in any event 3 months prior to beginning IVF treatment.
  • Smokers require higher amounts of fertility medications to stimulate their ovaries
  • Smokers have lower implantation rates than nonsmokers
  • Women who smoke require twice the same number of IVF attempts
  • Women who smoke experience more failed fertilisation cycles

Fertility Clinic

The fertility clinic you decide for the IVF treatment can enormously influence your IVF success. Variables to consider while assessing the success rate of the clinic include:

  • The training and experience of the IVF facility and staff
  • The live birth rate per IVF cycles began
  • The rate of patients pregnant with multiples (twins, trios or more)
  • The lab utilized by the center and the capabilities of their staff
  • The type of patients acknowledged at the center, all the more explicitly their age and fertility issue.

In Vitro Fertilization (IVF) is a fertility treatment in which an egg is implanted by sperm outside of the female’s body. The egg is embedded in the female’s uterus after a certain number of days (2-6) of growth.
IVF can be used in a variety of situations, including infertility, reproductive surrogacy, and . menopause.

It is the fact that menopause is an obstruction to further conception, IVF has allowed females to have a baby at age of 50 and above. IVF likewise gives females with beginning early menopausal a possibility. Females, whose uteruses have been appropriately prepared, can get Pregnant from an egg of an egg donor. Even after menopause initiates, the uterus is very fit for carrying an effective pregnancy.

Pregnancy After Menopause Using IVF

In females who are of childbearing age, there are five stages to IVF: stimulation, egg retrieval, insemination, and fertilization, embryo culture, and embryo transfer. However, on the grounds that females who have just experienced menopause are not delivering eggs, they don’t have to experience the initial two stages, and will rather need to utilize eggs from an egg donor.

Getting pregnant through IVF, similar to all pregnancies, accompanies risks. Yet, in case you’re generally healthy, an IVF-instigated pregnancy after menopause won’t really carry any new complications.

Pregnancy-related risks like high blood pressure, preeclampsia, infections, and preterm labor are the most common complications, but some women who try IVF after menopause don’t have to worry about particular problems linked to their older ages during pregnancy.
Since a youthful woman’s egg is used, the risk of chromosomal abnormalities is reduced. .

Egg Donation for IVF in Menopause

Donor egg and embryo transfer gives the most reasonable conceptive choice for older women who are either perimenopausal or menopausal and remains the best treatment of choice for patients of cutting edge reproductive age.

Oocyte donation from young donor reduces the issues of decreased ovarian reserve and expanded aneuploidy risk that goes with propelling age, and results in altogether higher pregnancy rates than standard IVF regimens.

Females over 45, even as old as 55, may achieve pregnancy rates similar to young females using their own eggs. When donated oocytes are used, recipient age has no effect on cycle outcomes, with fertilization rates, embryo implantation rates, and continuous pregnancy rates comparable to younger females.

Potential Risks of Pregnancy with IVF After Menopause

Pregnancy during perimenopause or postmenopause, while possible, poses some health dangers.
These hazards, which are similar to pregnancy risks for women over the age of 35, include:

  • Multiple pregnancies that may result in early birth, low birth weight, and troublesome delivery
  • Gestational diabetes, risking more medical conditions for both mother and infant
  • High blood pressure, that needs cautious observing and medication
  • Placenta previa, which may require bed rest, medicines, or cesarean delivery
  • Miscarriage or stillbirth
  • Cesarean birth
  • Premature or low birth weight
  • Chromosomal abnormalities are seen all the more regularly among kids born to older mothers.

As a woman ages, previous ailments can increase health risks for pregnancy and delivery. So prior to thinking of getting pregnant after menopause, consult a doctor who can assess your general health for IVF after menopause.

Best Age for an IVF Treatment

Age for IVF treatment – Infertility is a complicated issue that affects up to 15% of couples who are attempting to conceive. Depending on the individual circumstance, different infertility factors might be treated through in-vitro fertilization (IVF). IVF is usually effective, particularly for women under age 35 or for those who use donor eggs.

Infertility and Ageing

As indicated by the Society for Assisted Reproductive Technology, achievement rates for IVF decrease drastically after age 37, making age the main factor for women who want to pursue pregnancy utilizing their own eggs. After age 43, donated eggs from younger women are frequently needed for effective pregnancy.

As a woman ages, the excess eggs in her ovaries likewise age, making them less capable of fertilization and their embryos less fit for implants. Just 12 percent of the 300,000 eggs a female is born with remains at age 30, and just 9,000 eggs remain at age 40. Females who are perimenopausal ordinarily react ineffectively to ovarian stimulation medication and their live birth rates with IVF treatment are essentially lower than with younger females.

Effects of Age on Egg Quality and Quantity for IVF Treatment

  • IVF success rates utilizing their own eggs begin to drop at around 30 and drops quicker during the mid-30s and early 40s. This drop is due to diminishing egg quantity and quality.
  • Live births are uncommon at age 44 or more utilizing the female partner’s eggs. There is no drop in the progress rate with age when utilizing young donor eggs.
  • The age of the eggs is significant. The age of the recipient (uterine age) has almost no impact on progress rates when utilizing contributor eggs.
  • Most donors are in their 20’s – so the “egg age” is amazing with egg donation cycles.

IVF Success Rates According to Age

  • The success rate of IVF relies on the age of the woman going through treatment, as well as the reason for infertility (if it’s known).
  • Younger females are more likely to have a successful pregnancy. IVF isn’t typically suggested for females beyond 42 years of age as the odds of an effective pregnancy are believed to be excessively low.
  • Between 2014 and 2016 the level of IVF treatments that resulted in a live birth was:
    • 29% for women under 35
    • 23% for women of age 35 to 37
    • 15% for women of age 38 to 39
    • 9% for women of age 43 to 44
    • 2% for women of age more than 44
  • These figures are for females utilizing their own eggs and their partner’s sperm, utilizing the per embryo transferred measure.
  • Keeping up a healthy weight and avoiding alcohol, smoking and caffeine during treatment may improve your odds of having a child with IVF.